Revue de Pneumologie Clinique – Vol. 69 – N° 1 – p. – La maladie de Castleman: observations inhabituelles et revue de la littérature – EM|consulte. Disease definition. Castleman disease (CD) is a benign lymphoproliferative disorder that may present as a localized or multicentric form (see these terms). Introduction La maladie de Castleman (MC) est une affection rare, caractérisée par l’existence d’une forme localisée et d’une forme.

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The pathological features and the therapeutic management of CD are discussed. If you are a subscriber, please sign in ‘My Account’ at the top right of the screen. As per the Law relating to information storage and personal integrity, you have the right to oppose art 26 of that lawaccess art 34 of that law and rectify art 36 of that law your personal data. While surgery is the treatment for localized lesions, steroids and chemotherapy are indicated in the multicentric type.

J Infect Dis A herpesvirus of rhesus monkeys related to the human Kaposi’s sarcoma-associated herpesvirus.

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Human herpesvirus type 8 interleukin-6 homologue is functionally active on human myeloma cells. Remy-Jardin bcastlemqnA. Two forms have been described: HHV-8 is associated with plasmablastic variant of Castleman’s disease that is linked to HHV-8 positive plasmablastic lymphoma.

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Additional information Further information on this disease Classification s 2 Gene s 0 Other website s 6. The owners of this website hereby guarantee to respect the legal confidentiality conditions, applicable in France, and not to disclose this data to third parties.

Access to the text HTML. CT and MRI can help in the diagnosis, which is confirmed by histopathological assessment. Multicentric Castleman’s disease in HIV infection: Outline Masquer le plan. Akkad dB. Journal page Archives Contents list. Interleukin-6 family of cytokines and gp An unusual cluster of cases of Castleman’s disease during highly active antiretroviral therapy for AIDS. Castleman disease CD is a benign lymphoproliferative disorder that may present as a localized or multicentric form see these terms.

Access to the full text of this article requires a subscription. Only comments seeking to improve the quality and accuracy of information on the Orphanet website are accepted. They underlie the difficulty of surgical resection due to the tumor vascularization.

Both young patients were affected with an isolated ve localization of Castleman disease. The second one is characterized by an uncommon radiological presentation, with a calcification within the tumor. La maladie de Castleman: Casleman to the text HTML. Nous rapportons trois observations de maladie de Castleman unicentrique.

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Accueil du site de la malade de CASTLEMAN

For all other comments, please send your remarks via contact us. Top of the page – Article Outline. The clinical manifestations are heterogeneous, ranging from asymptomatic discrete lymphadenopathy to recurrent episodes of diffuse lymphadenopathy with severe systemic symptoms. Dysregulated interleukin 6 expression produces a syndrome resembling Castleman’s disease in mice. Because of the risk of relapse and malignant transformation, long-term follow-up is mandatory.

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Human herpesvirus 8 encodes a homolog of interleukin The third one is a plasma cell form with monoclonal proliferation associated with a monoclonal gammapathy. Exacerbations of clinical symptoms in human immunodeficiency virus type 1-infected patients with multicentric Castleman’s disease are associated with a high increase in Kaposi’s sarcoma herpesvirus DNA load in peripheral blood mononuclear cells.

Induction of B cell hyperplasia in simian immunodeficiency virus-infected rhesus macaques with the simian homologue of Kaposi’s sarcoma-associated herpesvirus. Scherpereel abcM.

Health care resources for this disease Expert centres Diagnostic tests 8 Patient organisations 36 Orphan drug s 4. Br J Haematol Castleman disease CD is a benign lymphoproliferative disorder, rare in children.

La maladie de Castleman : observations inhabituelles et revue de la littérature – EM|consulte

J Clin Invest Kaposi’s sarcoma-associated herpesvirus-like DNA sequences in multicentric Castleman’s disease. It can also be monocentric or multicentric. A report of two cases and a review of the literature.