13 Dec Hydrops fetalis is Latin for edema of the fetus. Ballantyne first described hydrops fetalis in , although this condition had been recognized. Hydrops fetalis is excessive extravasation of fluid into the third space in a fetus which could be due to heart failure, volume overload, decreased oncotic pressure. Hb Bart’s hydrops fetalis is the most severe form of alpha-thalassemia (see this term) and is almost always lethal. It is characterized by fetal onset of generalized .

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Ethnic influences are related almost entirely to cause. Acta Obstet Gynecol Scand. Vertically transmitted infection Neonatal infection Congenital rubella syndrome Neonatal herpes simplex Mycoplasma hominis infection Ureaplasma urealyticum infection Omphalitis Neonatal sepsis Group B streptococcal infection Neonatal conjunctivitis. Ultrasonographic studies demonstrate cerebral white matter damage, suggesting antenatal necrosis in approximately one third.

In some patients, it may also be associated with polyhydramnios and placental edema. Rh disease was previouslyconsidered the usual cause of fetal hydrops. ComiXology Thousands of Digital Comics.

Abnormalitas struktural yang mengganggu struktur sirkulasi fetoplasenta. Epidemiology United States data The precise incidence of hydrops fetalis is difficult to elucidate, because many cases are not detected prior to intrauterine fetal death and some cases may resolve spontaneously in utero.

Neonatal paroxysmal supraventricular tachycardia with hydrops. Figure 3 outlines the potential pathogenic processes that lead to nonimmune hydrops fetalis.

Learn more about Amazon Prime. The presence of normal fetal movements also rules out disorders of primary fetal akinesia 161718 see Table 2 in the Supplementary Appendix.

The reduced prevalence of RhD disease has hidops fetal hemolytic anemias secondary to maternal isoimmunization with other Rh-group and other blood group antigens more apparent. Immune hydrops Alloimmunisasi eritrosit maternal ibu hamil memiliki respon immunologik terhadap antigen paternal yang asing bagi ibu.


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Desilets V, Audibert F. Devastating sequelae of alloimmune thrombocytopenia: Respiratory Intrauterine hypoxia Infant respiratory distress syndrome Transient tachypnea of the newborn Meconium aspiration syndrome pleural disease Pneumothorax Pneumomediastinum Wilson—Mikity syndrome Bronchopulmonary dysplasia.

However, the most important single factor is the cause of the hydrops. Etiology of nonimmune hydrops fetalis: Unfortunately, automated modifications of this test are less specific and sensitive than the original Kleihauer-Betke test, and several newer tests have been proposed.

The fetus may bleed into the mother, and this hemorrhage may be severe enough to lead to fetal death or hydrops.

One study showed that mortality rate was highest among neonates with congenital anomalies Obstetrical Ultrasound Studies at 20 Weeks of Gestation. The finding of placental hydrops may occur hudrops both pulmonary and generalized lymphangiectasia.

Large effusions can compress the mediastinal vessels, cause upper body edema, and interfere with esophageal functioning to cause secondary polyhydramnios.

Pediatric Hydrops Fetalis

Cardiac Disease and Critical Care Medicine. Noonan syndrome autosomal dominant with variable penetrance. Currently, which fetal neural and hormonal mechanisms induce and maintain the redistribution of blood flow, and which mechanisms allow metabolic disorders to cause hydrops, are almost completely unknown.

When you click on a Sponsored Product ad, you will be taken to an Amazon detail page where you can learn more about the product and purchase it. Death due to high-output cardiac failure in fetal sacrococcygeal teratoma.

Hepatic tumors, volvulus, and meconium peritonitis promote hydrops through hypoproteinemia, and isolated defects of the abdominal wall cause lymphatic obstruction.

Most Popular Articles According to Pediatricians. Unilateral effusions indicate the presence of a process such as chylothorax. Pediatr Clin North Am. Blood-volume estimates in Coombs-test-positive infants. Hydrops is an end-stage process for numerous fetal diseases. Potential pathogenic mechanisms for hydrops induced by Down’s syndrome include chylothorax, intrinsic cardiac disease particularly atrioventricular canal defectsand congenital leukemia.


Krywko D, Shunkwiler S. The aortic annulus measured 4. Alexa Actionable Analytics for the Web. Hemolytic disease of the fetus and newborn due to intravenous drug use. Congenital structural anomalies of the heart may be present in as many as one in four infants with hydrops; both right-heart and left-heart anomalies, systolic-overload and diastolic-overload conditions, high-output conditions, and congestive situations are represented.

Meconium peritonitis is noted in tumor or mass causes and in the discussion of infectious causes.

Hydrops Fetalis by Sharon Simamora on Prezi

Enter your mobile number or email address below and we’ll send you a link to download the free Kindle App. Indirect Coomb test untuk menilai alloimunisasi b.

Sign Up It’s Free! Amniosentesis untuk menilai kariotipe janin dan parvovirus B19, CMV, hidroops. A sonogram of the pelvis Dapat diulang setiap minggu. Mortality and mortality figures vary, but in general, the mortality rate is high. The ascites may extend into the scrotum to form a hydrocele.

Orphanet: Hb Bart’s hydrops fetalis

Elevated levels of aldosterone, renin, norepinephrine, and angiotensin-I are likely to be secondary consequences. Other heritable fetaljs of RBC production are listed above, but none is very common. Little doubt appears to exist that hydrops will be linked with most such inborn errors of metabolism in the near future. Hydrops results from an increase in hydrostatic pressure due to obstruction of venous return by visceromegaly or cardiomyopathy, a decrease in oncotic pressure due to hepatic or renal dysfunction, an increase in lymphatic or blood-vessel permeability, and late-onset anemia.

The diameter of a normal ascending aorta for a fetus at 20 weeks of gestation is 2.